SR9011 powder Sarms Bodybuilding Increase Exercise Endurance Quick Effect 1379686-29-9

Product Name:SR9011
Synonym:3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide
CAS:1379686-29-9
Assay:99%
Appearance:White powder
Storage:Shading , Confined Preservation
Usage:For obesity, diabetes, dyslipidemia and cardiovascular disease
Molecular Fomular:C23H31ClN4O3S
Molecular Weight:479.04

SR9011 Description

SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB- with an EC50 ~790 nM and REV-ERB-with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB- and REV-ERB- play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. 

SR9011 Application

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic.

The new compounds known as SR9011 can increase laboratory metabolism, fat burning and muscle growth. Scientists at the Scripps Institute (TSRI) have successfully tested a drug called SR9011, In mice that initiate metabolism and lead to increased muscle development. In essence, this is a pill of the sport system. SR9011 changes the metabolic characteristics of skeletal muscle in a similar manner to the observed changes, Animal training has endurance. Basically, the drug sends a signal to the muscle and tells it to modify it Its metabolism. Half of the mice studied showed improved run endurance in terms of time and distance. Obviously, a small drug-like molecule can increase the metabolic rate of skeletal muscle, increase exercise tolerance.

SR9011 Powder Usage:

A new compound called SR9011 increases metabolism, fat burning, and muscle growth in the lab.Scientists at The Scripps Research Institute (TSRI) have successfully tested a drug, called SR9011,in mice that kickstarts metabolism and results in increased muscle development.Essentially, it’s an exercise regime in a pill.

SR9011 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed in animals that are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify its metabolism.

Are you SR9011 manufacturer?

Yes, we are SR9011 manufacturer. We can supply a varity of sarms products.

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