How YK11 Works?
In 2011, Yuichiro Kanno of Toho University published the results of an initial study on YK11, confirming that the rare compound was a SARM.
YK11 attaches itself to the AR (androgen receptor), but only inducts methods that lead to the traditional side effects of androgens such as growth of body hair and prostate and enhanced aggression – to a restricted degree.
Most SARMS have quite limited androgenic side effects, but frequently only quite few anabolic effects when likened to testosterone. But, this doesn’t occur for YK11 as reported in Biological and Pharmaceutical Bulletin in 2013.
Kanno tested C2C12 muscle cells and not lab animals or humans. It has been discovered that muscle cells produce more anabolic factors if exposed to 500 nmol (nanomoles) YK11 than if you expose the same muscle cells to 500 nmol DHT.
YK11 induces muscle cells to make more follistatin (more than DHT does) – a strong myostatin inhibitor. YK11 works through the androgen receptor.
With that said, YK11 can be as good as testosterone in terms of muscle strengthening, but minus the detrimental side effects.